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Tuesday, July 21, 2020 | History

2 edition of Aspects of the pharmacology of diphenylmethane laxatives (Bisacodyl, oxyphenisatin and phenolphalein derivatives). found in the catalog.

Aspects of the pharmacology of diphenylmethane laxatives (Bisacodyl, oxyphenisatin and phenolphalein derivatives).

Reidar Bredo Sund

Aspects of the pharmacology of diphenylmethane laxatives (Bisacodyl, oxyphenisatin and phenolphalein derivatives).

by Reidar Bredo Sund

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  • 33 Currently reading

Published by (University of Oslo) in Oslo [etc] .
Written in English


Edition Notes

At head of title: From the Department of Pharmacology, Institute of Pharmacy, University of Oslo.

ContributionsUniversitetet i Oslo. Department of Pharmacology.
ID Numbers
Open LibraryOL13961636M

* Items available from stock in Japan will be delivered in weeks. * Please contact us if you need further information. (Sales Dept Tel: / E-mail: [email protected]) * To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that we cannot offer bulk quantities for some products. Laxative, any drug used in the treatment of constipation to promote the evacuation of feces. Laxatives produce their effect by several mechanisms. The four main types of laxatives include: saline purgatives, fecal softeners, contact purgatives, and bulk laxatives. Saline purgatives are salts.

  The book is mainly devoted on describing the pharmacology, pharmacokinetics, uses, side effects and ways to improve the bioavailability for some of the most commonly used drugs. Laxatives are a type of medicine that can treat constipation. They're often used if lifestyle changes, such as increasing the amount of fibre in your diet, drinking plenty of fluid and taking regular exercise, have not helped. Laxatives are available to buy from pharmacies and supermarkets. They're also available on prescription from a doctor.

  The diuretic, a laxative and hypoglycaemic activity of the various extracts (viz. pet-ether, chloroform, methanol and aqueous extract) at the dose of mg/kg, p.o. were studied in Wistar albino. The foundation of treatment of constipation is dietary fiber or bulk-forming laxatives that provide 20 to 25 g/day of raw fiber. Irritable bowel syndrome (IBS) is one of the most common GI disorders characterized by lower abdominal pain, disturbed defecation, and bloating. Many .


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Aspects of the pharmacology of diphenylmethane laxatives (Bisacodyl, oxyphenisatin and phenolphalein derivatives) by Reidar Bredo Sund Download PDF EPUB FB2

Laxatives are an important drug class. They relieve constipation whilst not coming with overly burdened side effect and drug interaction profiles. However, their use needs to be considered in the wider clinical context as improper use – such as in intestinal obstruction or laxative overuse/abuse – can cause substantial problems.

diphenylmethane laxatives: members of a chemical class of laxative agents including phenolphthalein and bisacodyl.

Laxatives. Intestinal motility, as well as gastric motility, is determined by the tone of parasympathetic innervation. To substances that selectively stimulate intestinal motility include laxatives.

On the mechanism of action laxatives can be divided into four groups, the characteristics of which are presented in Table. [25]. Eric Scholar, in xPharm: The Comprehensive Pharmacology Reference, Introduction. Laxatives are a group of drugs that either accelerate fecal passage or decrease fecal consistency.

They are used primarily to treat term is often used interchangeably with cathartics, purgatives or evacuants, but there are subtle differences in the meaning especially between laxatives and.

Introduction: Diphenylmethane laxatives Description of Diphenylmethane laxatives Diphenylmethane laxatives: Related Topics. These medical condition or symptom topics may be relevant to medical information for Diphenylmethane laxatives: Chemical Class; Laxative Phenolphthalein; Bisacodyl.

Interesting Medical Articles: Symptoms of the Silent. Pharmacology of Laxatives. Annual Review of Pharmacology and Toxicology Vol. (Volume publication date April ) Annual Review of Pharmacology and Toxicology Pharmacology of Antidiarrheal Drugs F Awouters, C J E Niemegeers, and, and P A J Janssen.

Laxatives are use to treat constipation by accelerating peristalsis and there are different type of laxatives which are irritants and stimulants which cause irritation of the GI track resulting in. Diphenylmethane is recommended as a plasticizer to improve the dyeing properties, as a solvent for dyes, and as a dye carrier for printing with disperse dyes.

The addition of diphenylmethane to saturated, linear polyesters improves their thermal stability, and its addition to jet fuels increases their stability and lubricating properties.

Laxatives provide a temporary way to increase the motility of the bowel or soften up faecal matter. However, if misused or overused, they can cause problems, such as chronic constipation. Laxatives should not be used in people with a suspected bowel obstruction or appendicitis.

Overuse of laxatives and taking some laxatives, such as bulking. The book is clearly written and well illustrated and will give the reader a better understanding of the mechanisms of drug action as well as insight into the development of new drugs. Pharmacology of Intestinal Permeatioo-Edited by T.

Csaky. Handbook of Experimental Pharmacology, Vol parts I and II. Part I, pp. Aspects of the pharmacology of diphenylmethane laxatives (bisacodyl, oxyphenisatin and phenolphthalein derivatives) (a review) R.

Sund, Norvegica Pharm. Acta45, Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase.

is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started inthis collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters. While laxatives and stool softeners can help you overcome a bout of constipation, these medications come with side effects.

We’ll cover common side effects for short-term and long-term use of. Stimulants—Stimulant laxatives, also known as contact laxatives, encourage bowel movements by acting on the intestinal wall. They increase the muscle contractions that move along the stool mass.

Stimulant laxatives are a popular type of laxative for self-treatment. However, they also are more likely to cause side effects. Pharmacology is a branch of medicine and pharmaceutical sciences which is concerned with the study of drug or medication action, where a drug can be broadly or narrowly defined as any man-made, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to.

Bisacodyl (bis ak’ oh dil) is a mild laxative that is available over-the-counter and is commonly used to treat mild constipation and bowel irregularity.

Bisacodyl is believed to act by direct stimulation of intestinal peristalsis. Bisacodyl is a diphenylmethane derivative and is structurally similar to phenolphthalein. Casanthranol () Definition (NCI) A concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions.

Abstract. Laxatives are a heterogeneous group of drugs used to increase the frequency of bowel movements. They have been associated with two distinct effects on the gastrointestinal tract: a laxative-induced smooth muscle electric and motor pattern in the small bowel and an accumulation of fluid in the lumen of both the small and large intestines.

Start studying Constipation Pharmacology. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Stimulant laxatives/secretory laxatives/Cathartics Diphenylmethane derivative.

activates CIC-2 (Chloride channels type 2) on the apical aspect of GI epithelial cells producing a chloride-rich fluid secretion, which. Proprietary laxatives represent a multimillion dollar industry and are widely used by the apparently well population.

They are traditionally classified into bulk laxatives, lubricants, stimulants, stool softeners, and osmotic laxatives. The latter 3 probably act mainly by favouring accumulation of fluids and electrolytes in the lumen of the gut. Magnesium-containing saline laxatives are. Chapter Pharmacology of Antipsychotic Drugs.

Pharmacology Practice Questions: Drugs for Managing Psychosis. Practice question set # 1 (Side Effects of Antipsychotic Drugs) Practice question set #2 (General Classification and Properties I); Practice question set #3.Classification, pharmacology, and side-effects of common laxatives.

Müller-Lissner S(1). Author information: (1)Park-Klinik Weissensee, Berlin, Germany. No definition of the term laxative is satisfactory since their mode of actions affects multiple mechanisms, absorption/secretion and motor activity.

Laxatives are very heterogeneous chemically.Anthranoid laxatives are a group of naturally occurring laxatives which are commonly used in clinical practice and as a self‐medication for chronic constipation.

Although the short‐term use of these laxatives is generally safe, results from in vitro and animal studies suggest that they have a tumorigenic potential. Obviously, care should be.